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What are the benefits of Resveratrol?
On non human mammals, it has been shown to prevent and shrink cancer, has been shown to have strong antiviral anti-fungal properties. RevGenetics has seen studies that have also shown neuro-protective, anti-aging, anti-inflammatory and life-prolonging effects on subjects*.
Resveratrol and Angiogenesis.
Angiogenesis is required for most cancer tumors to grow beyond a 2-3 mm diameter. When delivered systemically, at a dose of 2.5-100mg per kg of body weight, Resveratrol has been found to inhibit the tumor activated neovascularization and wound healing. The suppression by Resveratrol could have a role in its effect on stopping tumor growth.
In Resveratrol obtained from dietary foods, such as red wine, their was some evidence of therapeutic effects. At higher doses that can be achieved through supplement concentrations and pharmacological sources, the protective effects and results were more dramatic. In one study, a dose of 40 mg per kg of body weight increased the survival of mice from 0% to 70% that had subcutaneous neuroblastomas.
Resveratrol and drug metabolism.
In studies using livers of Resveratrol treated rats, it has been found that it may prevent carcinogens while at the same time increasing the body's capacity to eliminate harmful molecules.
Resveratrol as Antioxidant.
Reactive oxygen species are shown to have a damaging role to DNA as well as other macromolecules. Resveratrol has a antioxidant capacity that can also be related to the chemo preventative effects it has shown. Resveratrol appears to prevent LDL oxidation in some studies. In stroke prone rats, Resveratrol significantly reduced oxidative stress markers.
Resveratrol and cholesterol
In 1982 Resveratrol was shown to inhibit the deposit of triglycerides and cholesterol in rat livers. Current studies are not conclusive.
Resveratrol and postmenopausal women
Resveratrol has been reported to act as a phytooestrogen in some systems. It has been suggested that it has helped the effects of it Cardioprotective effects. At this time the oestrogenic effects have been subjects of debate and research is working to see if there is a firm connection for the cardioprotective effects.
Resveratrol and immunity
Resveratrol has been shown to reduce and suppress many types of inflammation, which is a main interest in arthritis, psoriasis, and crohn's disease. Inflammation can also play a part in cardiovascular disease and cancer. Resveratrol could represent a positive alternative to current treatments for chronic inflammation as aspirin taken for long period can damage the lining of the stomach, while Resveratrol does not. In addition, Resveratrol enhances immune response in mice, as well as shown to protect them from infection by herpes simplex virus 1 and 2. This suggests Resveratrol interaction with the immune system is more complex, and that the immune system could even be
enhanced.
Other Resveratrol studies
Resveratrol has been reported to protect against hearing loss, act as an analgesic, reduce injury to spinal cord, liver, kidneys, lungs, intestine, and colon. The results indicate that Resveratrol is not limited to help against brain and heart injuries.
Studies we would like to see:
Because no comprehensive studies have been done for children regarding its effects on natural development, we do not recommend anyone under 18 take Resveratrol at this time.
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